Quote from American Heritage Dictionary:

"The act or process of causing to undergo alteration or change. An alteration or change as in nature, from or quality."

Description:

Mutation follows Barra Deval, the Atlantean Satan. MUTATION, the Great Event, is a pictogram of the heavy three tiered pyramid of body, mind and spirit sundered by the energetic action of the strongest planets. The Serplion is throwing the planets out of their orbits to shake loose a new mutation. Negative Saturn is still in the Serplion's mouth, while Jupiter, the planet of social structure, and aggressive Mars topple the pyramid into the water of the unconscious. Mercury (mind) and Venus (emotion) seemingly float on the water. The Fourth Sun and a small new Moon together with potential Man and Woman, can be seen joined in a seed capsule, waiting to be born into a further stage of cosmic learning.

Interpreted use:

Planetary powers are heavy, Accept and employ their energy. There is a new dimension ahead.

Reversed (card received upside down):

Do nothing until a new balance appears. There is great danger from uncontrollable deeper forces.